ELLEN DEGENERES kissed ROB LOWE on her show yesterday.  He was demonstrating how Jewel was disgusted by the idea of kissing him on a failed TV drama called "The Lyon's Den" back in 2003.

Rob asked Ellen to help him reenact the kiss, and it's amazing!

Here's the whole interview - the "Kiss" part starts at 1:34...

Also, who wouldn't want to kiss Rob Lowe!?

VALERIE MACON, GETTY IMAGES